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Lupita Infante is turning heartbreak into something communal on her latest release. The Mexican-American singer-songwriter joins forces with Chiquis for “Con Una, Dos o Tres,” a música mexicana collaboration built around the emotional aftermath of a breakup—and the confidence that eventually comes from surviving it.

Released September 17, the track brings together two women whose careers are deeply connected to Mexican music history while continuing to establish identities beyond their famous surnames. Streaming platforms list “Con Una, Dos o Tres” as the latest release from both artists. 

Co-written by Infante alongside J. Eduardo Murguia and Mauricio L. Arriaga, “Con Una, Dos o Tres” approaches heartbreak without romanticizing it. Instead, the song acknowledges the difficult stretch between losing a relationship and realizing that the pain is temporary. It is designed for the kind of night when tequila, mezcal or aguardiente—and the right company—can become part of the healing process.

“It’s a song for those moments when you’re going through the heartbreak of losing a relationship that you know is going to hurt, but you also know that the pain won’t last forever,” Infante said in announcing the release. “Ending a relationship is never easy, and you have to go through those difficult moments, but we recover and, in the end, we’re always okay.”

That perspective makes Chiquis a natural counterpart. Much of her own catalog has been built around resilience, independence and emotionally direct storytelling, giving “Con Una, Dos o Tres” a chemistry that extends beyond simply pairing two recognizable names.

The collaboration also carries another layer of significance. Infante is the granddaughter of Mexican icon Pedro Infante, while Chiquis is the daughter of Jenni Rivera. Following Infante’s collaboration with Leonardo Aguilar on “Amémonos de Nuevo,” the new single places her in creative conversation with another family whose history is inseparable from música mexicana.

Chiquis described the collaboration as both personal and generational, saying she and Infante are connected not only by their families’ contributions to Mexican music, but by their experiences as women working within the genre.

That distinction matters. Legacy can create visibility, but it can also become a creative constraint when every new release is measured against the history attached to an artist’s surname. Infante’s recent work increasingly suggests that she is using heritage as a foundation rather than an endpoint. Pairing with artists such as Aguilar and Chiquis allows her to acknowledge those traditions while building a contemporary network of artists carrying música mexicana forward.

The timing also fits a wider shift inside the genre. As música mexicana continues expanding beyond traditional geographic and generational boundaries, its growth is increasingly being defined not only by younger male stars and corridos, but by women reclaiming ranchera, banda and other traditional forms as vehicles for modern storytelling. “Con Una, Dos o Tres” operates in that space: its subject is timeless, but its perspective is rooted in female agency rather than heartbreak alone.

The single follows Infante’s fourth studio album, Aunque Me Duela, released in May. The eight-song project moves through ranchera and norteño influences and includes “Amémonos de Nuevo” with Leonardo Aguilar, “Con Todo Respeto” and “Prenderte una Vela.” 

In that context, “Con Una, Dos o Tres” feels less like an isolated collaboration and more like an extension of the album’s emotional language. Aunque Me Duela centered on accepting pain even when walking away is difficult; this new chapter moves further into what happens afterward. The heartbreak remains, but so does the ability to recover from it.

For Infante, that progression arrives alongside growing institutional recognition. The Latin Songwriters Hall of Fame has confirmed that she will receive the LA MUSA Elena Casals Award at its 13th annual LA MUSA Awards on October 14 at The Flamingo Theater in Miami. The organization says the honor recognizes her work preserving and advancing Mexican musical traditions while developing her own artistic identity and introducing that heritage to new generations. 

That recognition helps frame where Infante currently stands in her career. Rather than distancing herself from the legacy of Pedro Infante, she has increasingly positioned herself as part of its continuation while expanding what that lineage can sound like for a contemporary audience. Collaborations with Leonardo Aguilar and now Chiquis strengthen that positioning by connecting different branches of Mexican music history without reducing any of the artists involved to nostalgia.

“Con Una, Dos o Tres” ultimately works because its generational significance does not overwhelm its simpler purpose: it is a breakup song about getting through the part that hurts.

For Lupita Infante, however, the release also reinforces a larger trajectory. Between Aunque Me Duela, high-profile collaborations and her upcoming LA MUSA recognition, 2026 is becoming a year in which preserving tradition and establishing an individual identity are increasingly operating as the same mission.

As Lupita Infante continues expanding her own chapter in música mexicana, “Con Una, Dos o Tres” adds another piece to a year defined by collaboration, tradition and artistic independence. Follow LaMezcla.com and explore the LaMezcla Music App for more new releases and the artists shaping the next era of Latin music.

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